Heparin and cAMP modulators interact during pre-in vitro maturation to affect mouse and human oocyte meiosis and developmental competence
Author(s) -
Haitao Zeng,
Zheng Ren,
Luis Guzmán,
X. Wang,
Melanie L. SuttonMcDowall,
Lesley J. Ritter,
Michel De Vos,
Johan Smitz,
Jeremy G. Thompson,
Robert B. Gilchrist
Publication year - 2013
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/det086
Subject(s) - oocyte , in vitro maturation , biology , endocrinology , andrology , medicine , polycystic ovary , blastocyst , in vitro fertilisation , embryogenesis , embryo , microbiology and biotechnology , insulin resistance , insulin
Does heparin ablate the advantageous effects of cyclic adenosine mono-phosphate (cAMP) modulators during pre-in vitro maturation (IVM) and have a deleterious effect in standard oocyte IVM?
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