Haploinsufficiency of the paternal-effect gene Dnmt3L results in transient DNA hypomethylation in progenitor cells of the male germline
Author(s) -
Kirsten M. Niles,
Jonathan R. Yeh,
Donovan Chan,
Mylène Landry,
Makoto Nagano,
Jacquetta M. Trasler
Publication year - 2012
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/des395
Subject(s) - biology , dna methylation , epigenetics , haploinsufficiency , genetics , germ cell , reprogramming , methylation , andrology , gene , gene expression , phenotype , medicine
How does haploinsufficiency of the paternal-effect gene Dnmt3L affect DNA methylation establishment and stability in the male germline?
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