The scope, limitations and interpretation of copy number detection in the early embryo using the array CGH technique | Zendy

Paul N. Scriven | Zendy

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The scope, limitations and interpretation of copy number detection in the early embryo using the array CGH technique

Author(s) -

Paul N. Scriven

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/des366

Subject(s) - comparative genomic hybridization , scope (computer science) , biology , computational biology , embryo , genetics , chromosome , computer science , gene , programming language

In the current issue Mertzanidou et al. (2012) report a detailed chromosome study of cleavage-stage embryos using a version of the array comparative genomic hybridization (aCGH) technique. The aCGH technique is widely used in the genetics field and this study provides an opportunity to offer some guidance to the journal reader on its scope and limitations when applied to early human embryos, and the interpretation of the complex results sometimes obtained.

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