Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis | Zendy

Alexandra Vodolazkaia | Zendy; Y. El-Aalamat | Zendy; Dušan Popović | Zendy; Attila Mihalyi | Zendy; Xavier Bossuyt | Zendy; Cleophas Kyama | Zendy; Amelie Fassbender | Zendy; Attila Bokor | Zendy; Dominique Schols | Zendy; Dana Huskens | Zendy; Christel Meuleman | Zendy; Karen Peeraer | Zendy; Carla Tomassetti | Zendy; Olivier Gevaert | Zendy; Etienne Waelkens | Zendy; Ahmad Kasran | Zendy; Bart De Moor | Zendy; Thomas D’Hooghe | Zendy

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Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis

Author(s) -

Alexandra Vodolazkaia,

Y. El-Aalamat,

Dušan Popović,

Attila Mihalyi,

Xavier Bossuyt,

Cleophas Kyama,

Amelie Fassbender,

Attila Bokor,

Dominique Schols,

Dana Huskens,

Christel Meuleman,

Karen Peeraer,

Carla Tomassetti,

Olivier Gevaert,

Etienne Waelkens,

Ahmad Kasran,

Bart De Moor,

Thomas D’Hooghe

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/des234

Subject(s) - endometriosis , medicine , logistic regression , laparoscopy , follicular phase , univariate analysis , urology , gynecology , gastroenterology , radiology , multivariate analysis

At present, the only way to conclusively diagnose endometriosis is laparoscopic inspection, preferably with histological confirmation. This contributes to the delay in the diagnosis of endometriosis which is 6-11 years. So far non-invasive diagnostic approaches such as ultrasound (US), MRI or blood tests do not have sufficient diagnostic power. Our aim was to develop and validate a non-invasive diagnostic test with a high sensitivity (80% or more) for symptomatic endometriosis patients, without US evidence of endometriosis, since this is the group most in need of a non-invasive test.

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