Quantification of anti-Mullerian hormone (AMH) in dried blood spots: validation of a minimally invasive method for assessing ovarian reserve | Zendy

Thomas W. McDade | Zendy; Teresa K. Woodruff | Zendy; Yuan Huang | Zendy; William E. Funk | Zendy; Maureen Prewitt | Zendy; Laxmi A. Kondapalli | Zendy; Clarisa R. Gracia | Zendy

Open Access

Quantification of anti-Mullerian hormone (AMH) in dried blood spots: validation of a minimally invasive method for assessing ovarian reserve

Author(s) -

Thomas W. McDade,

Teresa K. Woodruff,

Yuan Huang,

William E. Funk,

Maureen Prewitt,

Laxmi A. Kondapalli,

Clarisa R. Gracia

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/des194

Subject(s) - anti müllerian hormone , ovarian reserve , infertility , medicine , andrology , physiology , hormone , biology , pregnancy , genetics

Biological markers of ovarian reserve have the potential to advance research on fecundability, infertility and reproductive aging. Anti-Müllerian hormone (AMH) has emerged as a clinically useful measure of ovarian reserve, but the requirement for venous blood is an obstacle to application in non-clinical settings. This paper validates a new method for quantifying AMH in dried blood spot (DBS) samples--drops of whole blood collected on filter paper following a simple finger stick.

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