No evidence of somatic DNA copy number alterations in eutopic and ectopic endometrial tissue in endometriosis | Zendy

Merli Saare | Zendy; Deniss Sõritsa | Zendy; Kadri Vaidla | Zendy; Priit Palta | Zendy; Maido Remm | Zendy; Maris Laan | Zendy; Helle Karro | Zendy; Andrei Sõritsa | Zendy; Andres Salumets | Zendy; Thomas D’Hooghe | Zendy; Maire Peters | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

No evidence of somatic DNA copy number alterations in eutopic and ectopic endometrial tissue in endometriosis

Author(s) -

Merli Saare,

Deniss Sõritsa,

Kadri Vaidla,

Priit Palta,

Maido Remm,

Maris Laan,

Helle Karro,

Andrei Sõritsa,

Andres Salumets,

Thomas D’Hooghe,

Maire Peters

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/des125

Subject(s) - endometriosis , somatic cell , loss of heterozygosity , population , biology , copy number variation , andrology , allele , cancer research , genetics , medicine , gene , genome , environmental health

De novo somatic copy number aberrations (SCNAs) in eutopic and ectopic endometria are thought to be involved in the pathogenesis of endometriosis. In this study we used, for the first time, high-density single nucleotide polymorphism-array technology for accurate detection of SCNAs, inherited DNA copy number variations (CNVs) and copy-neutral loss of heterozygosity (cn-LOH) patterns in patients with endometriosis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research