Assisted oocyte activation is not beneficial for all patients with a suspected oocyte-related activation deficiency | Zendy

F. Vanden Meerschaut | Zendy; Dimitra Nikiforaki | Zendy; Stefanie De Gheselle | Zendy; V. Dullaerts | Zendy; E. Van den Abbeel | Zendy; Jan Gerris | Zendy; Björn Heindryckx | Zendy; Petra De Sutter | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Assisted oocyte activation is not beneficial for all patients with a suspected oocyte-related activation deficiency

Author(s) -

F. Vanden Meerschaut,

Dimitra Nikiforaki,

Stefanie De Gheselle,

V. Dullaerts,

E. Van den Abbeel,

Jan Gerris,

Björn Heindryckx,

Petra De Sutter

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/des097

Subject(s) - human fertilization , oocyte activation , intracytoplasmic sperm injection , andrology , oocyte , sperm , pregnancy , fertilisation , medicine , biology , in vitro fertilisation , embryo , reproductive technology , genetics , lactation

Despite the success of ICSI, total fertilization failure (TFF) still occurs in 1-3% of all ICSI cycles. ICSI followed by assisted oocyte activation (ICSI-AOA) can restore fertilization, most efficiently in cases of sperm-related fertilization deficiency. The indication for ICSI-AOA is less obvious when the capacity of the sperm to activate oocytes is considered normal, as proved by a heterologous ICSI model, such as the mouse oocyte activation test (MOAT). In this study, we verified whether ICSI-AOA is beneficial for patients in whom an oocyte-related activation deficiency is suspected.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research