Gene variations in sex hormone pathways and the risk of testicular germ cell tumour: a case–parent triad study in a Norwegian–Swedish population | Zendy

Wenche Kristiansen | Zendy; Kristine Andreassen | Zendy; Robert Karlsson | Zendy; Elin L. Aschim | Zendy; Roy M. Bremnes | Zendy; O. Dahl | Zendy; Sophie D. Fosså | Zendy; Olbjørn Klepp | Zendy; Carl W. Langberg | Zendy; A. Solberg | Zendy; Steinar Tretli | Zendy; HansOlov Adami | Zendy; F. Wiklund | Zendy; Tom Grotmol | Zendy; Trine B. Haugen | Zendy

Open Access

Gene variations in sex hormone pathways and the risk of testicular germ cell tumour: a case–parent triad study in a Norwegian–Swedish population

Author(s) -

Wenche Kristiansen,

Kristine Andreassen,

Robert Karlsson,

Elin L. Aschim,

Roy M. Bremnes,

O. Dahl,

Sophie D. Fosså,

Olbjørn Klepp,

Carl W. Langberg,

A. Solberg,

Steinar Tretli,

HansOlov Adami,

F. Wiklund,

Tom Grotmol,

Trine B. Haugen

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/des075

Subject(s) - single nucleotide polymorphism , biology , genetics , oncology , odds ratio , case control study , population , medicine , gene , genotype , environmental health

Testicular germ cell tumour (TGCT) is the most common cancer in young men, and an imbalance between the estrogen and androgen levels in utero is hypothesized to influence TGCT risk. Thus, polymorphisms in genes involved in the action of sex hormones may contribute to variability in an individual's susceptibility to TGCT.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research