Circulating luteinizing hormone level after triggering oocyte maturation with GnRH agonist may predict oocyte yield in flexible GnRH antagonist protocol
Author(s) -
S.-L. Chen,
D.-S. Ye,
Xiaopan Chen,
Xiaoxue Yang,
Haiyan Zheng,
Yuting Tang,
Yuxia He,
Wei Guo
Publication year - 2012
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/des049
Subject(s) - oocyte , agonist , ovarian hyperstimulation syndrome , ovulation , medicine , endocrinology , luteinizing hormone , human fertilization , gonadotropin releasing hormone antagonist , andrology , gonadotropin releasing hormone , in vitro fertilisation , biology , hormone , pregnancy , embryo , receptor , anatomy , genetics , microbiology and biotechnology
The use of gonadotrophin-releasing hormone (GnRH) agonist for triggering final oocyte maturation and ovulation can reduce ovarian hyperstimulation syndrome (OHSS) in high-risk patients. LH levels post-trigger with GnRH agonist might be correlated with oocyte yield and maturity. Our aim was to evaluate the relationship between serum LH level at 12-h post-trigger and oocyte yield, maturity and fertilization rate in patients at high risk of OHSS and therefore who were treated with a flexible GnRH antagonist protocol in which final oocyte maturation was triggered with GnRH agonist.
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