Diet-induced paternal obesity in the absence of diabetes diminishes the reproductive health of two subsequent generations of mice | Zendy

Tod Fullston | Zendy; Nicole O. Palmer | Zendy; Julie A. Owens | Zendy; Megan Mitchell | Zendy; Hassan W. Bakos | Zendy; Michelle Lane | Zendy

Open Access

Diet-induced paternal obesity in the absence of diabetes diminishes the reproductive health of two subsequent generations of mice

Author(s) -

Tod Fullston,

Nicole O. Palmer,

Julie A. Owens,

Megan Mitchell,

Hassan W. Bakos,

Michelle Lane

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/des030

Subject(s) - offspring , biology , obesity , epigenome , gamete , infertility , physiology , sperm , endocrinology , genetics , pregnancy , dna methylation , gene , gene expression

Obesity and related conditions, notably subfertility, are increasingly prevalent. Paternal influences are known to influence offspring health outcome, but the impact of paternal obesity and subfertility on the reproductive health of subsequent generations has been overlooked.

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