The effect of the swim-up and hyaluronan-binding methods on the frequency of abnormal spermatozoa detected by FISH and SCSA in carriers of balanced chromosomal translocations | Zendy

Miluše Vozdová | Zendy; Kateřina Kašíková | Zendy; Eva Oráčová | Zendy; P. Přinosilová | Zendy; R. Rybar | Zendy; Věra Hořínová | Zendy; Renata Gaillyová | Zendy; Jiřı́ Rubeš | Zendy

Open Access

The effect of the swim-up and hyaluronan-binding methods on the frequency of abnormal spermatozoa detected by FISH and SCSA in carriers of balanced chromosomal translocations

Author(s) -

Miluše Vozdová,

Kateřina Kašíková,

Eva Oráčová,

P. Přinosilová,

R. Rybar,

Věra Hořínová,

Renata Gaillyová,

Jiřı́ Rubeš

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der445

Subject(s) - sperm , chromosomal translocation , biology , semen , andrology , robertsonian translocation , chromatin , aneuploidy , ploidy , fluorescence in situ hybridization , chromosome , karyotype , genetics , microbiology and biotechnology , dna , medicine , gene

The swim-up and hyaluronan (HA)-binding methods are used for the selection of good quality spermatozoa to improve pregnancy rates and embryo quality and to reduce the number of miscarriages after IVF. We evaluated whether the processing of sperm by these methods reduces the frequency of spermatozoa with abnormal karyotypes and altered chromatin quality in balanced translocation carriers.

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