Influence of prenatal organohalogen levels on infant male sexual development: sex hormone levels, testes volume and penile length | Zendy

Lisethe Meijer | Zendy; Albert Martijn | Zendy; J. Melessen | Zendy; Abraham Brouwer | Zendy; Jana M. Weiss | Zendy; Frank H. de Jong | Zendy; Pieter J.J. Sauer | Zendy

Open Access

Influence of prenatal organohalogen levels on infant male sexual development: sex hormone levels, testes volume and penile length

Author(s) -

Lisethe Meijer,

Albert Martijn,

J. Melessen,

Abraham Brouwer,

Jana M. Weiss,

Frank H. de Jong,

Pieter J.J. Sauer

Publication year - 2012

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der426

Subject(s) - hypospadias , anogenital distance , endocrine system , hormone , physiology , testosterone (patch) , endocrinology , fetus , sperm , medicine , sex hormone binding globulin , testicular volume , prenatal development , pregnancy , andrology , biology , androgen , secondary sex characteristic , in utero , anatomy , genetics

Prenatal exposure to endocrine disruptors, like organohalogen compounds (OHCs), might be responsible for the increased aberrations in human male sexual development (hypospadias, cryptorchidism, testicular cancer and fall in sperm count) observed over the past decades. This development is established during fetal life, and reflected in sex hormone levels, testes volume and penile length post-partum. The present study investigates the correlation between prenatal OHC levels and male sexual development outcomes.

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