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Intermediate and normal sized CGG repeat on the FMR1 gene does not negatively affect donor ovarian response
Author(s) -
Belén Lledó,
Jaime Guerrero,
J A Ortíz,
Ruth Morales,
Jorge Ten,
J. Llácer,
Juliette Gimenez,
Rafael Bernabéu
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der415
Subject(s) - oocyte , fmr1 , infertility , ovarian reserve , stimulation , andrology , medicine , biology , endocrinology , pregnancy , allele , genetics , gene , embryo
Fragile X syndrome is associated with low ovarian reserve and poor ovarian response. The aim of this study was to investigate whether CGG repeats on the fragile X mental retardation 1 (FMR1) gene have predictive value for ovarian response to stimulation with gonadotrophins and for clinical outcome in our oocyte donation program.

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