Identification and validation of novel serum markers for early diagnosis of endometriosis
Author(s) -
Rahul Gajbhiye,
Archana Sonawani,
Shagufta Khan,
Amol Ratnakar Suryawanshi,
Sandeep Kadam,
Neeta Warty,
Vivek Raut,
Vrinda V. Khole
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der410
Subject(s) - endometriosis , autoantibody , western blot , antigen , medicine , immunoassay , epitope , blot , antibody , immunology , chemistry , biochemistry , gene
Non-invasive diagnosis of endometriosis is urgently required to prevent the long delay between the onset of symptoms and diagnosis. A biomarker that possesses both high sensitivity and specificity is greatly required. Here, we describe the use of a proteomic approach to identify potential novel endometrial antigens using sera from endometriosis patients and healthy controls, with evaluation of biomarkers for non-invasive diagnosis of endometriosis.
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