The prevalence of chromosomal abnormalities in subgroups of infertile men | Zendy

E. C. Dul | Zendy; Henk Groen | Zendy; Conny M.A. van RavenswaaijArts | Zendy; T. Dijkhuizen | Zendy; Jannie van EchtenArends | Zendy; J. A. Land | Zendy

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The prevalence of chromosomal abnormalities in subgroups of infertile men

Author(s) -

E. C. Dul,

Henk Groen,

Conny M.A. van RavenswaaijArts,

T. Dijkhuizen,

Jannie van EchtenArends,

J. A. Land

Publication year - 2011

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der374

Subject(s) - azoospermia , chromosomal abnormality , medicine , male infertility , cohort , gynecology , sperm , chromosome abnormality , karyotype , infertility , abnormality , odds ratio , oligospermia , obstetrics , andrology , biology , pregnancy , chromosome , genetics , gene , psychiatry

The prevalence of chromosomal abnormalities is assumed to be higher in infertile men and inversely correlated with sperm concentration. Although guidelines advise karyotyping infertile men, karyotyping is costly, therefore it would be of benefit to identify men with the highest risk of chromosomal abnormalities, possibly by using parameters other than sperm concentration. The aim of this study was to evaluate several clinical parameters in azoospermic and non-azoospermic men, in order to assess the prevalence of chromosomal abnormalities in different subgroups of infertile men.

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