Cold-shock domain family member YB-1 expression in endometrium and endometriosis
Author(s) -
Cássia Gisele Terrassani Silveira,
Jean Krampe,
Brigitte Ruhland,
K. Diedrich,
Daniela Hornung,
A. Agic
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der368
Subject(s) - endometriosis , endometrium , cold shock domain , cell growth , oncogene , andrology , biology , apoptosis , cancer research , medicine , cell cycle , endocrinology , genetics , gene , rna
The Y-box-binding protein (YB-1) is described as a potential oncogene highly expressed in tumors and associated with increased cell survival, proliferation, migration and anti-apoptotic signaling. The aim of our study was to examine the expression and role of YB-1 in human endometriosis (Eo) and its association with cell survival, proliferation and invasion.
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