Open AccessA survey of small RNAs in human sperm
Author(s) -
Stephen A. Krawetz,
Adéle Kruger,
Claudia Lalancette,
Rebecca Tagett,
Ester Antón,
Sorin Drăghici,
Michael P. Diamond
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der329
Subject(s) - sperm , biology , andrology , gynecology , genetics , medicine
There has been substantial interest in assessing whether RNAs (mRNAs and sncRNAs, i.e. small non-coding) delivered from mammalian spermatozoa play a functional role in early embryo development. While the cadre of spermatozoal mRNAs has been characterized, comparatively little is known about the distribution or function of the estimated 24,000 sncRNAs within each normal human spermatozoon.
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