Open AccessAn imbalance in interleukin-17-producing T and Foxp3+ regulatory T cells in women with idiopathic recurrent pregnancy loss
Author(s) -
S.K. Lee,
J.Y. Kim,
Sung Eun Hur,
C.J. Kim,
B.J. Na,
M. Lee,
Alice GilmanSachs,
Joanne KwakKim
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der301
Subject(s) - foxp3 , interleukin 17 , immunology , immune system , t cell , tumor necrosis factor alpha , regulatory t cell , interleukin , medicine , endocrinology , biology , il 2 receptor , cytokine
T cells which produce interleukin (IL)-17 are involved in chronic inflammatory processes and regulatory T (Treg) cells are possibly the most important immune regulators. We aimed to investigate peripheral blood IL-17(+) T and Foxp3(+) Treg cells in women with idiopathic recurrent pregnancy loss (RPL).