Gene expression profiling of peripheral blood mononuclear cells in endometriosis identifies genes altered in non-gynaecologic chronic inflammatory diseases | Zendy

Davide Gentilini | Zendy; A Perino | Zendy; Paola Viganò | Zendy; I. Chiodo | Zendy; Gaspare Cucinella | Zendy; M. Vignali | Zendy; A. M. Di Blasio | Zendy; Mauro Busacca | Zendy

Open Access

Gene expression profiling of peripheral blood mononuclear cells in endometriosis identifies genes altered in non-gynaecologic chronic inflammatory diseases

Author(s) -

Davide Gentilini,

A Perino,

Paola Viganò,

I. Chiodo,

Gaspare Cucinella,

M. Vignali,

A. M. Di Blasio,

Mauro Busacca

Publication year - 2011

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der270

Subject(s) - endometriosis , peripheral blood mononuclear cell , microarray , gene expression , gene expression profiling , immunology , biology , gene , oncogene , microarray analysis techniques , population , medicine , pathology , cell cycle , genetics , environmental health , in vitro

Pelvic inflammatory phenomena have been suggested as critical players in the natural history of endometriosis. However, to what extent these events could affect the systemic immunologic status remains to be clarified. Here, we compared the gene expression profile in peripheral blood mononuclear cells from endometriosis patients in the severe diseased stage with the profile after a conventional surgical treatment for removal of endometriotic lesions and adhesions.

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