Expression patterns of Aurora A and B kinases, Ki-67 and the estrogen and progesterone receptors determined using an endometriosis tissue microarray model | Zendy

Angelo Calcagno | Zendy; Tiziana Grassi | Zendy; Laura Mariuzzi | Zendy; Stefania Marzinotto | Zendy; Ambrogio P. Londero | Zendy; Maria ­Orsaria | Zendy; Carlo Alberto Beltrami | Zendy; D. Marchesoni | Zendy

Open Access

Expression patterns of Aurora A and B kinases, Ki-67 and the estrogen and progesterone receptors determined using an endometriosis tissue microarray model

Author(s) -

Angelo Calcagno,

Tiziana Grassi,

Laura Mariuzzi,

Stefania Marzinotto,

Ambrogio P. Londero,

Maria Orsaria,

Carlo Alberto Beltrami,

D. Marchesoni

Publication year - 2011

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der264

Subject(s) - endometriosis , endometrium , progesterone receptor , estrogen receptor , kinase , estrogen , medicine , aurora b kinase , tissue microarray , immunohistochemistry , biology , endocrinology , cancer research , cancer , cell , microbiology and biotechnology , breast cancer , genetics , cell division , spindle apparatus

The roles of cell proliferation and genomic instability in endometriosis are highly debated aspects of the pathogenesis of this disease. Aurora A and B kinases play different important roles in cell cycle control and genomic instability and have never been studied in endometriosis. The aim of this study was to compare the expression levels of Aurora kinases, Ki-67 and hormone receptor in endometriotic tissue (ET) and normal endometrium.

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