Light-mediated activation reveals a key role for protein kinase A and sarcoma protein kinase in the development of sperm hyper-activated motility | Zendy

Shiran Shahar | Zendy; Amir Wiser | Zendy; Debbi Ickowicz | Zendy; Rachel Lubart | Zendy; Adrian Shulman | Zendy; Haim Breitbart | Zendy

Open Access

Light-mediated activation reveals a key role for protein kinase A and sarcoma protein kinase in the development of sperm hyper-activated motility

Author(s) -

Shiran Shahar,

Amir Wiser,

Debbi Ickowicz,

Rachel Lubart,

Adrian Shulman,

Haim Breitbart

Publication year - 2011

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der232

Subject(s) - hyperactivation , capacitation , motility , sperm motility , sperm , microbiology and biotechnology , human fertilization , protein kinase a , kinase , biology , andrology , chemistry , genetics , medicine

Hyper-activated motility (HAM) is part of the sperm capacitation process, which is necessary for fertilization. In this study, we investigated the effect of visible light on sperm motility and hyperactivation and evaluated pathways mediating these effects.

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