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Lymphangiogenesis in deep infiltrating endometriosis
Author(s) -
Susanne Keichel,
Maria Luisa Barcena,
Uta Reichelt,
Wolfram F. J. Riedlinger,
Achim Schneider,
Christhardt Köhler,
Sylvia Mechsner
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der230
Subject(s) - endometriosis , medicine , lymphangiogenesis , lymph , lymphatic system , stromal cell , pathology , immunohistochemistry , lymphatic vessel , metastasis , cancer
In patients diagnosed with deep infiltrating endometriosis (DIE), foci of endometriosis are detected in mesorectal lymph nodes (LNs) after segmental bowel resection and in pelvic sentinel LNs. Lymph vessels (LVs) seem to be the possible routes for the dissemination of endometriotic cells from DIE-lesions to LN. Therefore, we conducted a study to investigate the occurrence and density of LV and lymphangiogenic growth factors in DIE.

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