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Animal age, weight and estrus cycle stage impact the quality of in vitro grown follicles
Author(s) -
Jennifer HirshfeldCytron,
Francesca E. Duncan,
Ming Xu,
Jennifer K. Jozefik,
Lonnie D. Shea,
Teresa K. Woodruff
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der183
Subject(s) - biology , follicle , estrous cycle , ovarian follicle , andrology , endocrinology , medicine , population , anti müllerian hormone , follicle stimulating hormone , menstrual cycle , hormone , luteinizing hormone , environmental health
Ovarian tissue cryopreservation is an emerging fertility preservation option, and culturing follicles isolated from this tissue to obtain mature gametes may ultimately be the best solution for patients for whom transplantation is contraindicated. It is unclear, however, how patient-specific variables (including age, weight and menstrual cycle stage) impact follicle growth and quality during three-dimensional culture.

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