DHEA as a miracle drug in the treatment of poor responders; hype or hope? | Zendy

Kayhan Yakın | Zendy; Bülent Urman | Zendy

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DHEA as a miracle drug in the treatment of poor responders; hype or hope?

Author(s) -

Kayhan Yakın,

Bülent Urman

Publication year - 2011

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der150

Subject(s) - dehydroepiandrosterone , miracle , poor responder , medicine , drug , warrant , endocrinology , pharmacology , gynecology , intensive care medicine , androgen , hormone , political science , financial economics , law , economics

Dehydroepiandrosterone (DHEA) is being presented as a miracle-drug for the treatment of women responding poorly to gonadotrophin stimulation, while the debate on its actual effectiveness is still ongoing. We would like to present how insufficient the current evidence of acceptable quality is to warrant a conclusion that DHEA supplementation is an effective treatment for women with diminished ovarian reserve. We believe that large-scale, well-designed confirmatory studies are necessary to prove the efficacy of DHEA before it can be recommended for routine use.

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