Effect of reproductive tract environment following controlled ovarian hyperstimulation treatment on embryo development and global transcriptome profile of blastocysts: implications for animal breeding and human assisted reproduction | Zendy

Ahmed Gad | Zendy; U. Besenfelder | Zendy; F. Rings | Zendy; Nasser Ghanem | Zendy; Dessie SalilewWondim | Zendy; M.M. Hossain | Zendy; Dawit Tesfaye | Zendy; P. Lonergan | Zendy; Astrid Becker | Zendy; U Cinar | Zendy; K. Schellander | Zendy; V. Havlíček | Zendy; Michael Hölker | Zendy

Open Access

Effect of reproductive tract environment following controlled ovarian hyperstimulation treatment on embryo development and global transcriptome profile of blastocysts: implications for animal breeding and human assisted reproduction

Author(s) -

Ahmed Gad,

U. Besenfelder,

F. Rings,

Nasser Ghanem,

Dessie SalilewWondim,

M.M. Hossain,

Dawit Tesfaye,

P. Lonergan,

Astrid Becker,

U Cinar,

K. Schellander,

V. Havlíček,

Michael Hölker

Publication year - 2011

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der110

Subject(s) - oviduct , biology , blastocyst , transcriptome , embryo , andrology , ovulation , embryogenesis , reproductive technology , endocrinology , gene expression , hormone , gene , genetics , medicine

In mammals, the reproductive tract plays a crucial role in the success of early reproductive events and provides an optimal microenvironment for early embryonic development. However, changes in the reproductive tract environment associated with controlled ovarian hyperstimulation and the influence on the embryo transcriptome profile have not been investigated. Therefore, we investigated differences in the development rate and the transcriptome profile of bovine blastocysts developing in the reproductive tract of unstimulated or superovulated heifers.

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