Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa
Author(s) -
Martin Blomberg Jensen,
Poul Jannik Bjerrum,
Torben E. Jessen,
John E. Nielsen,
Ulla Nordström Joensen,
Inge A. Olesen,
Jørgen Holm Petersen,
Anders Juul,
Steen Dissing,
Niels Jørgensen
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der059
Subject(s) - endocrinology , medicine , sperm motility , calcium , acrosome reaction , sperm , motility , semen , biology , vitamin d and neurology , andrology , calcium in biology , population , semen quality , microbiology and biotechnology , environmental health
The vitamin D receptor (VDR) is expressed in human spermatozoa, and VDR-knockout mice and vitamin D (VD) deficiency in rodents results in impaired fertility, low sperm counts and a low number of motile spermatozoa. We investigated the role of activated VD (1,25(OH)(2)D(3)) in human spermatozoa and whether VD serum levels are associated with semen quality.
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