Cumulus cell gene expression predicts better cleavage-stage embryo or blastocyst development and pregnancy for ICSI patients | Zendy

Sandra Wathlet | Zendy; Tom Adriaenssens | Zendy; Ingrid Segers | Zendy; Greta Verheyen | Zendy; H. Van de Velde | Zendy; Wim Coucke | Zendy; Rabotnikova El | Zendy; Paul Devroey | Zendy; Johan Smitz | Zendy

Open Access

Cumulus cell gene expression predicts better cleavage-stage embryo or blastocyst development and pregnancy for ICSI patients

Author(s) -

Sandra Wathlet,

Tom Adriaenssens,

Ingrid Segers,

Greta Verheyen,

H. Van de Velde,

Wim Coucke,

Rabotnikova El,

Paul Devroey,

Johan Smitz

Publication year - 2011

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/der036

Subject(s) - blastocyst , andrology , oocyte , gene expression , embryo , biology , embryogenesis , gene , pregnancy , genetics , medicine

Cumulus cell (CC) gene expression is suggested as a non-invasive analysis method to predict oocyte competence. There are, however, important between-patient differences in CC gene expression. These can be compensated when expression results are combined with patient and cycle characteristics using a multiple regression analysis model.

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