EphrinA1 stimulates cell attachment and inhibits cell aggregation through the EphA receptor pathway in human endometrial carcinoma-derived Ishikawa cells
Author(s) -
Haruko Fujii,
Hiroshi Fujiwara,
Akihito Horie,
K. Suginami,
Yukiyasu Sato,
Ikuo Konishi
Publication year - 2011
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/der034
Subject(s) - erythropoietin producing hepatocellular (eph) receptor , microbiology and biotechnology , cell , cell culture , stromal cell , chemistry , receptor , cell adhesion , phosphorylation , focal adhesion , biology , cancer research , receptor tyrosine kinase , biochemistry , genetics
Recently, the Eph-ephrinA system was proposed to contribute to the initial interaction between the maternal endometrial epithelium and embryonic trophectoderm. Since the Eph-ephrin interaction can induce adhesive and/or repulsive forces into the cells, we examined the possible role of this system in functional changes in endometrial epithelial cells using endometrial carcinoma-derived Ishikawa cells.
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