Hormonal regulation of endometrial olfactomedin expression and its suppressive effect on spheroid attachment onto endometrial epithelial cells | Zendy

Suranga P. Kodithuwakku | Zendy; Ppy Ng | Zendy; Yaowen Liu | Zendy; Ernest Hung Yu Ng | Zendy; William S.B. Yeung | Zendy; Patrick Ho | Zendy; Ckf Lee | Zendy

Open Access

Hormonal regulation of endometrial olfactomedin expression and its suppressive effect on spheroid attachment onto endometrial epithelial cells

Author(s) -

Suranga P. Kodithuwakku,

Ppy Ng,

Yaowen Liu,

Ernest Hung Yu Ng,

William S.B. Yeung,

Patrick Ho,

Ckf Lee

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq298

Subject(s) - endometrium , stromal cell , trophoblast , andrology , biology , immunohistochemistry , embryo , medicine , endocrinology , microbiology and biotechnology , cancer research , fetus , placenta , immunology , pregnancy , genetics

Olfactomedin (Olfm) is a member of a diverse group of extracellular matrix proteins important for neuronal growth. Recent microarray studies identified Olfm as one of the down-regulated transcripts in receptive endometrium at the time of embryo attachment and implantation. However, the underlying molecular mechanisms that govern Olfm expression and its effect on embryo attachment and implantation remain unknown.

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