Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus | Zendy

Sung Tae Kim | Zendy; K. Marquard | Zendy; Sahar Stephens | Zendy; Erica Louden | Zendy; Jenifer E. Allsworth | Zendy; Kelle H. Moley | Zendy

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Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus

Author(s) -

Sung Tae Kim,

K. Marquard,

Sahar Stephens,

Erica Louden,

Jenifer E. Allsworth,

Kelle H. Moley

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq292

Subject(s) - adiponectin , embryo , uterus , receptor , endocrinology , biology , medicine , andrology , microbiology and biotechnology , obesity , insulin resistance

Adiponectin (Adipoq), a protein secreted by adipocytes in inverse proportion to the adipose mass present, modulates energy homeostasis and increases insulin sensitivity. Tissue Adipoq signaling decreases in settings of maternal diabetes, polycystic ovary syndrome (PCOS) and endometriosis, conditions which are associated with reproductive difficulty. Our objective was to define the expression and hormonal regulation of Adipoq and its receptors in the mouse preimplantation embryo and uterus.

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