Low-dose aspirin therapy and hypertensive pregnancy complications in unselected IVF and ICSI patients: a randomized, placebo-controlled, double-blind study
Author(s) -
Mervi Haapsamo,
H. Martikainen,
Helena Tinkanen,
Seppo Hein,
S. Nuojua-Huttunen,
Juha Räsänen
Publication year - 2010
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deq286
Subject(s) - aspirin , medicine , placebo , pregnancy , randomized controlled trial , obstetrics , incidence (geometry) , gynecology , surgery , physics , alternative medicine , pathology , biology , optics , genetics
Low-dose aspirin therapy could improve remodelling of maternal spiral arteries during early placentation and prevent subsequent pregnancy-related hypertensive disorders. We investigated whether low-dose aspirin therapy reduces the incidence of hypertensive pregnancy complications in unselected IVF and ICSI patients when medication was started prior to pregnancy.
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