Sex hormone-binding globulin concentrations before conception as a predictor for gestational diabetes in women with polycystic ovary syndrome | Zendy

Susanne M. Veltman-Verhulst | Zendy; Timon W. van Haeften | Zendy; Marinus J.C. Eijkemans | Zendy; Harold W. de Valk | Zendy; Bart C.J.M. Fauser | Zendy; Anne Goverde | Zendy

Open Access

Sex hormone-binding globulin concentrations before conception as a predictor for gestational diabetes in women with polycystic ovary syndrome

Author(s) -

Susanne M. Veltman-Verhulst,

Timon W. van Haeften,

Marinus J.C. Eijkemans,

Harold W. de Valk,

Bart C.J.M. Fauser,

Anne Goverde

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq272

Subject(s) - sex hormone binding globulin , polycystic ovary , gestational diabetes , insulin resistance , medicine , endocrinology , free androgen index , waist , odds ratio , pregnancy , obstetrics , insulin , body mass index , gestation , biology , hormone , androgen , genetics

Low plasma sex hormone-binding globulin (SHBG) concentrations during pregnancy have been associated with the risk of developing gestational diabetes mellitus (GDM). Women presenting with polycystic ovary syndrome (PCOS) often exhibit low plasma SHBG concentration and are at increased risk of developing GDM. In this study, we investigate whether SHBG levels before conception are predictive of GDM in women with PCOS.

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