Effect of dienogest administration on angiogenesis and hemodynamics in a rat endometrial autograft model | Zendy

H. Katayama | Zendy; Tomihiro Katayama | Zendy; Kazuhiko Uematsu | Zendy; M Hiratsuka | Zendy; Masaki Kiyomura | Zendy; Yutaka Shimizu | Zendy; Atsunori Sugita | Zendy; Masanori Ito | Zendy

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Effect of dienogest administration on angiogenesis and hemodynamics in a rat endometrial autograft model

Author(s) -

H. Katayama,

Tomihiro Katayama,

Kazuhiko Uematsu,

M Hiratsuka,

Masaki Kiyomura,

Yutaka Shimizu,

Atsunori Sugita,

Masanori Ito

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq241

Subject(s) - angiogenesis , dienogest , endometrium , microvessel , in vivo , neovascularization , microcirculation , transplantation , endometriosis , medicine , endocrinology , andrology , urology , biology , microbiology and biotechnology

We aimed to establish an endometrial autograft model in rats that would allow for repetitive in vivo analyses of angiogenesis. Dienogest (DNG) is an orally active progestin used for the treatment of endometriosis. We investigated whether DNG would affect angiogenesis of the ectopic endometrium in our model.

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