Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma | Zendy

Khaleque Newaz Khan | Zendy; Michio Kitajima | Zendy; Koichi Hiraki | Zendy; Akira Fujishita | Zendy; Masahiro Nakashima | Zendy; Tetsuya Ishimaru | Zendy; Hideaki Masuzaki | Zendy

Open Access

Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma

Author(s) -

Khaleque Newaz Khan,

Michio Kitajima,

Koichi Hiraki,

Akira Fujishita,

Masahiro Nakashima,

Tetsuya Ishimaru,

Hideaki Masuzaki

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq240

Subject(s) - adenomyosis , endometriosis , gnrhr , medicine , endometrium , proliferation index , endometrial biopsy , uterus , immunohistochemistry , endocrinology , pathology , gonadotropin releasing hormone , hormone , luteinizing hormone

We recently demonstrated the effect of gonadotrophin-releasing hormone agonist (GnRHa) on tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma. Here, we investigated expression of GnRH receptors (GnRHRs) and effect of GnRHa on the proliferation of cells derived from endometria and pathological lesions of women with these reproductive diseases.

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