Oxygen consumption and ROS production are increased at the time of fertilization and cell cleavage in bovine zygotes | Zendy

A. S. Lopes | Zendy; Michelle Lane | Zendy; Jeremy G. Thompson | Zendy

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Oxygen consumption and ROS production are increased at the time of fertilization and cell cleavage in bovine zygotes

Author(s) -

A. S. Lopes,

Michelle Lane,

Jeremy G. Thompson

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq221

Subject(s) - zygote , human fertilization , andrology , oxygen , embryo , cleavage (geology) , biology , sperm , embryogenesis , microbiology and biotechnology , chemistry , anatomy , medicine , paleontology , organic chemistry , fracture (geology)

Oxygen consumption is a key indicator of metabolic activity within embryos. Increased oxidative activity and REDOX changes at the time of fertilization have been suggested to signal Ca(2+) oscillations after sperm penetration. The objective of the present study was to determine the oxygen consumption and the REDOX status of zygotes and early embryos at the time of sperm penetration and cell cleavage and to investigate how metabolism relates to key temporal events and developmental competence.

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