High risk men's perceptions of pre-implantation genetic diagnosis for hereditary breast and ovarian cancer
Author(s) -
Gwendolyn P. Quinn,
Susan T. Vadaparampil,
Cheryl A. Miree,
JiHyun Lee,
Xiuhua Zhao,
Susan Friedman,
Susan Yi,
J. Mayer
Publication year - 2010
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deq207
Subject(s) - brca mutation , logistic regression , demography , population , gynecology , medicine , genetic testing , risk perception , breast cancer , psychology , family medicine , cancer , perception , environmental health , neuroscience , sociology
Pre-implantation genetic diagnosis (PGD) is an assisted reproductive technology procedure which provides parents with the option of conducting genetic analyses to determine if a mutation is present in an embryo. Though studies have discussed perceptions of PGD from a general population, couples or high-risk women, no studies to date have specifically examined PGD usage among men. This study sought to explore perceptions and attitudes towards PGD among males who either carry a BRCA mutation or have a partner or first degree relative with a BRCA mutation.
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