Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos | Zendy

Štefan Číkoš | Zendy; J. Kenneth Burkus | Zendy; Alexandra Bukovská | Zendy; Dušan Fabián | Zendy; P Rehák | Zendy; Juraj Koppel | Zendy

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Expression of adiponectin receptors and effects of adiponectin isoforms in mouse preimplantation embryos

Author(s) -

Štefan Číkoš,

J. Kenneth Burkus,

Alexandra Bukovská,

Dušan Fabián,

P Rehák,

Juraj Koppel

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq193

Subject(s) - adiponectin , blastocyst , embryo , adiponectin receptor 1 , endocrinology , medicine , biology , receptor , adipose tissue , andrology , embryogenesis , microbiology and biotechnology , insulin , insulin resistance

Adiponectin, a pleiotropic hormone secreted from adipose tissue, can mediate some negative effects of obesity on female health, and can participate in the impaired reproductive performance of obese women. Using a mouse model, we investigated expression of adiponectin receptors in ovulated oocytes and in vivo derived preimplantation embryos, and tested effects of different adiponectin isoforms on development of preimplantation embryos in vitro.

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