Evaluating the necessity for universal screening of prospective oocyte donors using enhanced genetic and psychological testing
Author(s) -
A. Reh,
Alana Amarosa,
Frederick Licciardi,
L.C. Krey,
Alan S. Berkeley,
Lisa Kump
Publication year - 2010
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deq182
Subject(s) - minnesota multiphasic personality inventory , oocyte , medicine , genetic testing , gynecology , personality , family medicine , psychology , psychiatry , obstetrics , clinical psychology , biology , genetics , social psychology , embryo
To minimize the potential for harmful inheritable conditions, donors are rigorously screened according to standard guidelines, yet such guidelines may not be sufficient to exclude egg donors with certain known inheritable conditions. We compared universal screening of oocyte donors with Tay-Sachs, Fragile X, karyotype and Minnesota Multiphasic Personality Inventory-2 (MMPI-2) versus standard American Society of Reproductive Medicine (ASRM) guidelines that do not include such testing.
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