In humans, zona pellucida glycoprotein-1 binds to spermatozoa and induces acrosomal exocytosis | Zendy

Anasua Ganguly | Zendy; Antonín Bukovský | Zendy; Raj Kumar Sharma | Zendy; Pankaj Bansal | Zendy; Beena Bhandari | Zendy; Gupta Sk | Zendy

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In humans, zona pellucida glycoprotein-1 binds to spermatozoa and induces acrosomal exocytosis

Author(s) -

Anasua Ganguly,

Antonín Bukovský,

Raj Kumar Sharma,

Pankaj Bansal,

Beena Bhandari,

Gupta Sk

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq105

Subject(s) - zona pellucida , zona pellucida glycoprotein , glycoprotein , human fertilization , exocytosis , microbiology and biotechnology , andrology , biology , chemistry , oocyte , embryo , endocrinology , anatomy , medicine , secretion

It has been suggested that the zona pellucida (ZP) may mediate species-specific fertilization. In human the ZP is composed of four glycoproteins: ZP1, ZP2, ZP3 and ZP4. In the present study, the expression profile of ZP1 in human oocytes and ovaries, and its role during fertilization, is presented.

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