Altered aquaporin expression in women with polycystic ovary syndrome: hyperandrogenism in follicular fluid inhibits aquaporin-9 in granulosa cells through the phosphatidylinositol 3-kinase pathway | Zendy

Fan Qu | Zendy; F. F. Wang | Zendy; Xi-Ping Lu | Zendy; Mengyuan Dong | Zendy; JianZhong Sheng | Zendy; Pengpeng Lv | Zendy; Guolian Ding | Zendy; Biwei Shi | Zendy; Di Zhang | Zendy; Hefeng Huang | Zendy

Open Access

Altered aquaporin expression in women with polycystic ovary syndrome: hyperandrogenism in follicular fluid inhibits aquaporin-9 in granulosa cells through the phosphatidylinositol 3-kinase pathway

Author(s) -

Fan Qu,

F. F. Wang,

Xi-Ping Lu,

Mengyuan Dong,

JianZhong Sheng,

Pengpeng Lv,

Guolian Ding,

Biwei Shi,

Di Zhang,

Hefeng Huang

Publication year - 2010

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deq078

Subject(s) - polycystic ovary , endocrinology , hyperandrogenism , medicine , dihydrotestosterone , follicular phase , testosterone (patch) , androgen , sex hormone binding globulin , follicular fluid , ovary , biology , chemistry , hormone , insulin resistance , insulin , embryo , oocyte , microbiology and biotechnology

The present study was designed to evaluate whether the alteration of aquaporin-9 (AQP-9) expression in granulosa cells (GCs) of patients with polycystic ovary syndrome (PCOS) was associated with the hyperandrogenism in follicular fluid (FF).

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