ESX1 gene expression as a robust marker of residual spermatogenesis in azoospermic men
Author(s) -
E. Bonaparte,
M Moretti,
Giovanni M. Colpi,
F Nerva,
G. Contalbi,
L. Vaccalluzzo,
Silvia Tabano,
Francesca Romana Grati,
Giacomo Gazzano,
Silvia Maria Sirchia,
Giuseppe Simoni,
A. Gallina,
Monica Miozzo
Publication year - 2010
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deq074
Subject(s) - testicular sperm extraction , azoospermia , spermatogenesis , obstructive azoospermia , biology , andrology , sperm retrieval , sperm , spermatocyte , context (archaeology) , intracytoplasmic sperm injection , germ cell , meiosis , endocrinology , medicine , infertility , gene , genetics , pregnancy , paleontology
It would be of value to identify ongoing spermatogenesis molecular markers which can predict successful sperm recovery in patients with non-obstructive azoospermia undergoing conventional or microsurgical testicular sperm extraction (TESE/microTESE). ESX1 is an X-linked homeobox gene expressed in testis, placenta, brain and lung in humans and specifically in pre- and post-meiotic germ cells of the testis in mice.
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