Open AccessEffects of oral and vaginal administration of levonorgestrel emergency contraception on markers of endometrial receptivity
Author(s) -
ChunXia Meng,
Lena Marions,
Birgitta Byström,
Kristina GemzellDanielsson
Publication year - 2010
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deq007
Subject(s) - levonorgestrel , endometrium , medicine , endocrinology , emergency contraception , regimen , menstrual cycle , population , andrology , hormone , environmental health , family planning , research methodology
The standard regimen of the levonorgestrel-only pill (1.5 mg either in a single dose or in a dose of 0.75 mg twice, 12 h apart) administered orally for emergency contraception (EC) has been shown to have no effect on endometrial development and markers of endometrial receptivity. We aimed to explore whether repeated oral and single vaginal administration of levonorgestrel affect the endometrium and thus potentially increase the EC efficacy, compared with the standard regimen.