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Influence of peritoneal fluid on the expression of angiogenic and proteolytic factors in cultures of endometrial cells from women with endometriosis
Author(s) -
R. Cosín,
Juan Gilabert–Estellés,
Luis Ramón,
M.J. Gómez-Lechón,
M. Chirivella,
Aitana BrazaBoïls,
Francisco España,
A. Estellés
Publication year - 2009
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dep419
Subject(s) - endometriosis , peritoneal fluid , angiogenesis , endometrium , plasminogen activator , vascular endothelial growth factor , endometrial cancer , medicine , matrix metalloproteinase , endocrinology , cancer research , andrology , cancer , vegf receptors
Endometriosis, defined as the presence of endometrium outside the uterus, is one of the most frequent benign gynaecological diseases. It has been suggested that both endometrial and peritoneal factors, related to angiogenesis and proteolysis, can be implicated in this disease. The aim of this study was to evaluate the influence of peritoneal fluid on the expression of angiogenic and proteolytic factors in cultures of endometrial cells from women with and without endometriosis.

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