Open AccessExpression of eicosanoid biosynthetic and catabolic enzymes in peritoneal endometriosis
Author(s) -
J. C. Lousse,
Sylvie Defrère,
S. Colette,
Anne Van Langendonckt,
Jacques Donnez
Publication year - 2009
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dep408
Subject(s) - eicosanoid , endometriosis , catabolism , enzyme , inflammation , biology , medicine , endocrinology , immunology , biochemistry , arachidonic acid
Increased peritoneal eicosanoid concentrations have been reported in endometriosis patients and might be important in disease-associated pain and inflammation. Here, we evaluated the expression of key biosynthetic and catabolic enzymes involved in this abnormal eicosanoid production in peritoneal macrophages and endometriotic lesions.
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