Suppression of follicular rupture with meloxicam, a cyclooxygenase-2 inhibitor: potential for emergency contraception | Zendy

C. Jesam | Zendy; A.M. Salvatierra | Zendy; J. L. Schwartz | Zendy; H.B. Croxatto | Zendy

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Suppression of follicular rupture with meloxicam, a cyclooxygenase-2 inhibitor: potential for emergency contraception

Author(s) -

C. Jesam,

A.M. Salvatierra,

J. L. Schwartz,

H.B. Croxatto

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep392

Subject(s) - meloxicam , emergency contraception , cyclooxygenase , medicine , follicular phase , andrology , gynecology , family planning , pharmacology , population , endocrinology , research methodology , biology , enzyme , environmental health , biochemistry

There is evidence that cyclooxygenase-2 (COX-2) inhibitors can prevent or delay follicular rupture. COX-2 inhibitors, such as meloxicam, may offer advantages over emergency contraception with levonorgestrel, such as extending the therapeutic window for up to 24 h. We assessed the effect of meloxicam administered in the late follicular phase upon ovulation in women.

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