Increased risk of blastogenesis birth defects, arising in the first 4 weeks of pregnancy, after assisted reproductive technologies | Zendy

Jane Halliday | Zendy; Obioha C. Ukoumunne | Zendy; H.W.G. Baker | Zendy; Sue Breheny | Zendy; AM Jaques | Zendy; Claire Garrett | Zendy; D. Healy | Zendy; David J. Amor | Zendy

Open Access

Increased risk of blastogenesis birth defects, arising in the first 4 weeks of pregnancy, after assisted reproductive technologies

Author(s) -

Jane Halliday,

Obioha C. Ukoumunne,

H.W.G. Baker,

Sue Breheny,

AM Jaques,

Claire Garrett,

D. Healy,

David J. Amor

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep364

Subject(s) - pregnancy , assisted reproductive technology , reproductive technology , obstetrics , medicine , gynecology , reproductive biology , biology , infertility , genetics , lactation

The reasons for increased birth defect prevalence following in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are largely unknown. Classification of birth defects by pathology rather than organ system, and examination of the role of embryo freezing and thawing may provide clues to the mechanisms involved. This study aimed to investigate these two factors.

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