The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa | Zendy

J. Zhang | Zendy; Xinyuan Ding | Zendy; Z Bian | Zendy; Yankai Xia | Zendy; Chuncheng Lu | Zendy; Shoujun Wang | Zendy; Ling Song | Zendy; X. Wang | Zendy

Open Access

The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa

Author(s) -

J. Zhang,

Xinyuan Ding,

Z Bian,

Yankai Xia,

Chuncheng Lu,

Shoujun Wang,

Ling Song,

X. Wang

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep356

Subject(s) - acrosome reaction , sperm , calcium , acrosome , capacitation , biology , ionophore , calcium in biology , antibody , semen , andrology , oocyte , spermatozoon , intracellular , human fertilization , sperm motility , microbiology and biotechnology , medicine , immunology , anatomy , embryo , botany

Before a spermatozoon can fertilize an oocyte it must undergo a cascade of biochemical and physiological changes that facilitate its binding and penetration into the oocyte. Epididymal protease inhibitor (eppin) has been found to play a critical role in male fertility through an immunological approach.

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