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Embryonic stem cell-like cells derived from adult human testis
Author(s) -
Sefika C Mizrak,
J.V. Chikhovskaya,
Hooman SadriArdekani,
Silke F. van Daalen,
Cindy M. Korver,
Suzanne Hovingh,
Hermien L. RoepersGajadien,
Ángel Raya,
Kees Fluiter,
T.M. De Reijke,
Jean de la Rosette,
Alida C. Knegt,
Juan Carlos Izpisúa Belmonte,
Fulco van der Veen,
Dirk G. de Rooij,
Sjoerd Repping,
Ans M. M. van Pelt
Publication year - 2009
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dep354
Subject(s) - embryonic stem cell , stem cell , multipotent stem cell , microbiology and biotechnology , regenerative medicine , adult stem cell , biology , amniotic epithelial cells , kosr , genetics , progenitor cell , gene
Given the significant drawbacks of using human embryonic stem (hES) cells for regenerative medicine, the search for alternative sources of multipotent cells is ongoing. Studies in mice have shown that multipotent ES-like cells can be derived from neonatal and adult testis. Here we report the derivation of ES-like cells from adult human testis.

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