A new culture technique that allows in vitro meiotic prophase development of fetal human oocytes | Zendy

Miguel A. BrieñoEnríquez | Zendy; Pedro Robles | Zendy; Raquel Garcia-Cruz | Zendy; Ignasi Roig | Zendy; L. Cabero | Zendy; Flavio Martı́nez | Zendy; M. Garcı́a | Zendy

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A new culture technique that allows in vitro meiotic prophase development of fetal human oocytes

Author(s) -

Miguel A. BrieñoEnríquez,

Pedro Robles,

Raquel Garcia-Cruz,

Ignasi Roig,

L. Cabero,

Flavio Martı́nez,

M. Garcı́a

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep351

Subject(s) - synapsis , meiosis , biology , oocyte , andrology , homologous recombination , in vitro , synaptonemal complex , oogenesis , homologous chromosome , prophase , microbiology and biotechnology , genetics , embryo , medicine , dna , gene

Little is known about the mechanisms that regulate meiosis in the human female fetus as a result of the technical difficulties in obtaining samples. Currently, there is no technique for human fetal oocyte culture that permits the maintenance of fetal ovarian tissue in vitro which allows the progression of meiosis in a reproducible and standardized way.

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