The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis | Zendy

Ayako Watanabe | Zendy; Fuminori Taniguchi | Zendy; Masao Izawa | Zendy; Kana Suou | Zendy; Takashi Uegaki | Zendy; Eri Takai | Zendy; Naoki Terakawa | Zendy; Takashi Harada | Zendy

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The role of survivin in the resistance of endometriotic stromal cells to drug-induced apoptosis

Author(s) -

Ayako Watanabe,

Fuminori Taniguchi,

Masao Izawa,

Kana Suou,

Takashi Uegaki,

Eri Takai,

Naoki Terakawa,

Takashi Harada

Publication year - 2009

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dep305

Subject(s) - survivin , stromal cell , xiap , inhibitor of apoptosis , apoptosis , gene silencing , cancer research , ectopic expression , biology , endometriosis , microbiology and biotechnology , caspase , medicine , cell culture , gene , programmed cell death , genetics

Decreased susceptibility of endometrial tissue to apoptosis may contribute to the pathogenesis of endometriosis. We investigate the role of survivin in the pathophysiology of endometriosis through the ability of ectopic and eutopic endometrial stromal cells (ESCs) to resist apoptosis.

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